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Anomalies in the analysis of calibrated data

Anomalies in the analysis of calibrated data

This study examines the effects of calibration errors on model assumptions and data-analytic tools in direct calibration assays. These effects encompass induced dependencies, inflated variances, and heteroscedasticity among the calibrated measurements, whose distributions arise as mixtures. These anomalies adversely affect conventional inferences, including the inconsistency of sample means; the underestimation …