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Mathematical Analysis of a General Two-Patch Model of Tuberculosis Disease with Lost Sight Individuals

Mathematical Analysis of a General Two-Patch Model of Tuberculosis Disease with Lost Sight Individuals

A two-patch model,<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:msub><mml:mrow><mml:mi>S</mml:mi><mml:mi>E</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mn>1</mml:mn></mml:mrow></mml:msub><mml:mo>,…,</mml:mo><mml:msub><mml:mrow><mml:mi>E</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mi>n</mml:mi></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:msub><mml:mrow><mml:mi>L</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub></mml:math>, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>1,2</mml:mn></mml:math>, is used to analyze the spread of tuberculosis, with an arbitrary number<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M3"><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:math>of latently infected compartments in each patch. A fraction of infectious individuals that begun their treatment will not return to the hospital for the examination of sputum. This fact …