A Mathematical Model Quantifies Proliferation and Motility Effects of TGF‐β on Cancer Cells
A Mathematical Model Quantifies Proliferation and Motility Effects of TGF‐β on Cancer Cells
Transforming growth factor (TGF)-β is known to have properties of both a tumour suppressor and a tumour promoter. While it inhibits cell proliferation, it also increases cell motility and decreases cell-cell adhesion. Coupling mathematical modelling and experiments, we investigate the growth and motility of oncogene-expressing human mammary epithelial cells under …