On-lattice agent-based simulation of populations of cells within the open-source Chaste framework
On-lattice agent-based simulation of populations of cells within the open-source Chaste framework
Over the years, agent-based models have been developed that combine cell division and reinforced random walks of cells on a regular lattice, reaction–diffusion equations for nutrients and growth factors; and ordinary differential equations for the subcellular networks regulating the cell cycle. When linked to a vascular layer, this multiple scale …