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A patient-specific computational model of hypoxia-modulated radiation resistance in glioblastoma using <sup>18</sup> F-FMISO-PET
Glioblastoma multiforme (GBM) is a highly invasive primary brain tumour that has poor prognosis despite aggressive treatment. A hallmark of these tumours is diffuse invasion into the surrounding brain, necessitating a multi-modal treatment approach, including surgery, radiation and chemotherapy. We have previously demonstrated the ability of our model to predict …