A Cautionary Note About Estimating Effects of Secondary Exposures in Cohort Studies
A Cautionary Note About Estimating Effects of Secondary Exposures in Cohort Studies
Cohort studies are often enriched for a primary exposure of interest to improve cost-effectiveness, which presents analytical challenges not commonly discussed in epidemiology. In this paper, we use causal diagrams to represent exposure-enriched cohort studies, illustrate a scenario wherein the risk ratio for the effect of a secondary exposure on …