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Added predictive value of high-throughput molecular data to clinical data and its validation

Added predictive value of high-throughput molecular data to clinical data and its validation

Hundreds of ā€˜molecular signaturesā€™ have been proposed in the literature to predict patient outcome in clinical settings from high-dimensional data, many of which eventually failed to get validated. Validation of such molecular research findings is thus becoming an increasingly important branch of clinical bioinformatics. Moreover, in practice well-known clinical predictors ā€¦