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Identifying Subjects Who Benefit from Additional Information for Better Prediction of the Outcome Variables

Identifying Subjects Who Benefit from Additional Information for Better Prediction of the Outcome Variables

Suppose that we are interested in using new bio- or clinical markers, in addition to the conventional markers, to improve prediction or diagnosis of the patient's clinical outcome. The incremental value from the new markers is typically assessed by averaging across patients in the entire study population. However, when measuring …