The impact of cell crowding and active cell movement on vascular tumour growth
The impact of cell crowding and active cell movement on vascular tumour growth
A multiscale model for vascular tumour growth is presented which includes systems of ordinary differential equations for the cell cycle and regulation of apoptosis in individual cells, coupled to partial differential equations for the spatio-temporal dynamics of nutrient and key signalling chemicals. Furthermore, these subcellular and tissue layers are incorporated …