Observation of fragile-to-strong dynamic crossover in protein hydration water
Observation of fragile-to-strong dynamic crossover in protein hydration water
At low temperatures proteins exist in a glassy state, a state which has no conformational flexibility and shows no biological functions. In a hydrated protein, at and above 220 K, this flexibility is restored and the protein is able to sample more conformational sub-states, thus becomes biologically functional. This 'dynamical' …