Transcriptional Bursting in Gene Expression: Analytical Results for General Stochastic Models
Transcriptional Bursting in Gene Expression: Analytical Results for General Stochastic Models
Gene expression in individual cells is highly variable and sporadic, often resulting in the synthesis of mRNAs and proteins in bursts. Such bursting has important consequences for cell-fate decisions in diverse processes ranging from HIV-1 viral infections to stem-cell differentiation. It is generally assumed that bursts are geometrically distributed and …