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Design of sequentially randomized trials for testing adaptive treatment strategies

Design of sequentially randomized trials for testing adaptive treatment strategies

An adaptive treatment strategy (ATS) is an outcomeā€guided algorithm that allows personalized treatment of complex diseases based on patients' disease status and treatment history. Conditions such as AIDS, depression, and cancer usually require several stages of treatment because of the chronic, multifactorial nature of illness progression and management. Sequential multiple ā€¦