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VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain

VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain

The latest Ebola virus (EBOV) epidemic spread rapidly through Guinea, Sierra Leone, and Liberia, creating a global public health crisis and accelerating the assessment of experimental therapeutics and vaccines in clinical trials. One of those vaccines is based on recombinant vesicular stomatitis virus expressing the EBOV glycoprotein (VSV-EBOV), a live-attenuated …