Exploring single-sample SNP and INDEL calling with whole-genome <i>de novo</i> assembly
Exploring single-sample SNP and INDEL calling with whole-genome <i>de novo</i> assembly
Abstract Motivation: Eugene Myers in his string graph paper suggested that in a string graph or equivalently a unitig graph, any path spells a valid assembly. As a string/unitig graph also encodes every valid assembly of reads, such a graph, provided that it can be constructed correctly, is in fact …