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Funnel Landscape and Mutational Robustness as a Result of Evolution under Thermal Noise

Funnel Landscape and Mutational Robustness as a Result of Evolution under Thermal Noise

Using a statistical-mechanical model of spins, the evolution of phenotype dynamics is studied. Configurations of spins and their interaction $\mathbit{J}$ represent the phenotype and genotype, respectively. The fitness for selection of $\mathbit{J}$ is given by the equilibrium spin configurations determined by a Hamiltonian with $\mathbit{J}$ under thermal noise. The genotype …