Target prediction and a statistical sampling algorithm for RNA–RNA interaction
Target prediction and a statistical sampling algorithm for RNA–RNA interaction
Abstract Motivation: It has been proven that the accessibility of the target sites has a critical influence on RNA–RNA binding, in general and the specificity and efficiency of miRNAs and siRNAs, in particular. Recently, O(N6) time and O(N4) space dynamic programming (DP) algorithms have become available that compute the partition …