Learning to Live With Missing Quality-of-Life Data in Advanced-Stage Disease Trials
Learning to Live With Missing Quality-of-Life Data in Advanced-Stage Disease Trials
In advanced-stage disease, palliation can be the most important objective. Quality-of-life (QoL) outcomes provide an intuitively reasonable way to monitor palliation from the patient’s perspective. However, patients with advanced-stage disease are often unable to complete a series of QoL assessments because of deteriorating health. This introduces a possible bias in …