Estimating Disease Prevalence Using Relatives of Case and Control Probands
Estimating Disease Prevalence Using Relatives of Case and Control Probands
We introduce a method of estimating disease prevalence from case-control family study data. Case-control family studies are performed to investigate the familial aggregation of disease; families are sampled via either a case or a control proband, and the resulting data contain information on disease status and covariates for the probands …