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SUMMARY MEASURES AND STATISTICS FOR COMPARISON OF QUALITY OF LIFE IN A CLINICAL TRIAL OF CANCER THERAPY

SUMMARY MEASURES AND STATISTICS FOR COMPARISON OF QUALITY OF LIFE IN A CLINICAL TRIAL OF CANCER THERAPY

Assessment of health related quality of life (QOL) has become an important endpoint in many clinical trials of cancer therapy. Most of these studies entail multiple QOL scales that are assessed repeatedly over time. As a result, the problem of multiple comparisons is a primary analytic challenge with these trials. …