Basic Concepts and Methods for Joint Models of Longitudinal and Survival Data
Basic Concepts and Methods for Joint Models of Longitudinal and Survival Data
Joint models for longitudinal and survival data are particularly relevant to many cancer clinical trials and observational studies in which longitudinal biomarkers (eg, circulating tumor cells, immune response to a vaccine, and quality-of-life measurements) may be highly associated with time to event, such as relapse-free survival or overall survival. In …