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Brain–Tumor Interaction Biophysical Models for Medical Image Registration

Brain–Tumor Interaction Biophysical Models for Medical Image Registration

State-of-the art algorithms for deformable image registration are based on the minimization of an image similarity functional that is regularized by adding a penalty term on the deformation map. The penalty function typically represents a smoothness regularization. In this article, we use a constrained optimization formulation in which the image …