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Generalized Poland–Scheraga model for DNA hybridization

Generalized Poland–Scheraga model for DNA hybridization

The Poland-Scheraga (PS) model for the helix-coil transition of DNA considers the statistical mechanics of the binding (or hybridization) of two complementary strands of DNA of equal length, with the restriction that only bases with the same index along the strands are allowed to bind. In this article, we extend …