P2โ399: Structured total least squares for volumes of distribution estimation in PET imaging
P2โ399: Structured total least squares for volumes of distribution estimation in PET imaging
The volume distribution (DV), an index for amyloid deposition, is routinely estimated by the Graphical analysis (GA) for PiB (Pittsburgh Compound-B)- Positron emission tomography (PET) studies of Alzheimer's disease (AD). We found that the well-known bias of the GA estimated DV is primarily due to model error and noise in โฆ