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Non-Ignorable Missing Covariate Data in Survival Analysis: A Case-Study of an International Breast Cancer Study Group Trial

Non-Ignorable Missing Covariate Data in Survival Analysis: A Case-Study of an International Breast Cancer Study Group Trial

Summary Non-ignorable missing data, a serious problem in both clinical trials and observational studies, can lead to biased inferences. Quality-of-life measures have become increasingly popular in clinical trials. However, these measures are often incompletely observed, and investigators may suspect that missing quality-of-life data are likely to be non-ignorable. Although several …