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Nonparametric Estimation of Asymptomatic Duration from a Randomized Prospective Cancer Screening Trial

Nonparametric Estimation of Asymptomatic Duration from a Randomized Prospective Cancer Screening Trial

Summary We propose a nonparametric estimation of preclinical duration distribution in cancer based on data from a randomized early detection trial. In cancer screening studies, the preclinical duration of a disease is of great interest for better understanding the natural history of the disease, and for developing optimal screening strategies. …