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Three-dimensional coherent X-ray diffractive imaging of whole frozen-hydrated cells

Three-dimensional coherent X-ray diffractive imaging of whole frozen-hydrated cells

A structural understanding of whole cells in three dimensions at high spatial resolution remains a significant challenge and, in the case of X-rays, has been limited by radiation damage. By alleviating this limitation, cryogenic coherent diffractive imaging (cryo-CDI) can in principle be used to bridge the important resolution gap between …