Non‐parametric estimators of a monotonic dose–response curve and bootstrap confidence intervals
Non‐parametric estimators of a monotonic dose–response curve and bootstrap confidence intervals
Abstract In this paper we consider study designs which include a placebo and an active control group as well as several dose groups of a new drug. A monotonically increasing dose–response function is assumed, and the objective is to estimate a dose with equivalent response to the active control group, …