Stochastic differential equation models for ion channel noise in Hodgkin-Huxley neurons
Stochastic differential equation models for ion channel noise in Hodgkin-Huxley neurons
The random transitions of ion channels between conducting and nonconducting states generate a source of internal fluctuations in a neuron, known as channel noise. The standard method for modeling the states of ion channels nonlinearly couples continuous-time Markov chains to a differential equation for voltage. Beginning with the work of …