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Importance of Many-Body Effects in the Kernel of Hemoglobin for Ligand Binding

Importance of Many-Body Effects in the Kernel of Hemoglobin for Ligand Binding

We propose a mechanism for binding of diatomic ligands to heme based on a dynamical orbital selection process. This scenario may be described as bonding determined by local valence fluctuations. We support this model using linear-scaling first-principles calculations, in combination with dynamical mean-field theory, applied to heme, the kernel of …