The Effects of Tertiary and Quaternary Infections on the Epidemiology of Dengue
The Effects of Tertiary and Quaternary Infections on the Epidemiology of Dengue
The epidemiology of dengue is characterised by irregular epidemic outbreaks and desynchronised dynamics of its four co-circulating virus serotypes. Whilst infection by one serotype appears to convey life-long protection to homologous infection, it is believed to be a risk factor for severe disease manifestations upon secondary, heterologous infection due to …