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Dose–Response Modeling Under Simple Order Restrictions Using Bayesian Variable Selection Methods

Dose–Response Modeling Under Simple Order Restrictions Using Bayesian Variable Selection Methods

AbstractBayesian modeling of dose–response data offers the possibility to establish the relationship between a clinical or a genomic response and increasing doses of a therapeutic compound and to determine the nature of the relationship wherever it exists. In this article, we focus on an order-restricted one-way ANOVA model which can …