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Estimating Individualized Treatment Rules Using Outcome Weighted Learning

Estimating Individualized Treatment Rules Using Outcome Weighted Learning

Abstract There is increasing interest in discovering individualized treatment rules (ITRs) for patients who have heterogeneous responses to treatment. In particular, one aims to find an optimal ITR that is a deterministic function of patient-specific characteristics maximizing expected clinical outcome. In this article, we first show that estimating such an …