Systems biology of pro‐angiogenic therapies targeting the VEGF system
Systems biology of pro‐angiogenic therapies targeting the VEGF system
Abstract Vascular endothelial growth factor (VEGF) is a family of cytokines for which the dysregulation of expression is involved in many diseases; for some, excess VEGF causes pathological hypervascularization, while for others VEGF‐induced vascular remodeling may alleviate ischemia and/or hypoxia. Anti‐angiogenic therapies attacking the VEGF pathway have begun to live …