Minimize the Use of Minimization with Unequal Allocation
Minimize the Use of Minimization with Unequal Allocation
Summary Minimization as an alternative to randomization is gaining popularity for small clinical trials. In response to critics' questions about the proper analysis of such a trial, proponents have argued that a rerandomization approach, akin to a permutation test with conventional randomization, can be used. However, they add that this …