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Simple solvation potential for coarse‐grained models of proteins

Simple solvation potential for coarse‐grained models of proteins

Abstract We formulate a simple solvation potential based on a coarsed‐grained representation of amino acids with two spheres modeling the C α atom and an effective side‐chain centroid. The potential relies on a new method for estimating the buried area of residues, based on counting the effective number of burying …