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Clustering and Optimal Arrangement of Enzymes in Reaction-Diffusion Systems

Clustering and Optimal Arrangement of Enzymes in Reaction-Diffusion Systems

Enzymes within biochemical pathways are often colocalized, yet the consequences of specific spatial enzyme arrangements remain poorly understood. We study the impact of enzyme arrangement on reaction efficiency within a reaction-diffusion model. The optimal arrangement transitions from a cluster to a distributed profile as a single parameter, which controls the …