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The brachymorph mouse and the developmental‐genetic basis for canalization and morphological integration

The brachymorph mouse and the developmental‐genetic basis for canalization and morphological integration

SUMMARY Although it is well known that many mutations influence phenotypic variability as well as the mean, the underlying mechanisms for variability effects are very poorly understood. The brachymorph ( bm ) phenotype results from an autosomal recessive mutation in the phosphoadenosine‐phosphosulfate synthetase 2 gene ( Papps2 ). A major …