Prevalence, Characteristics, and Publication of Discontinued Randomized Trials
Prevalence, Characteristics, and Publication of Discontinued Randomized Trials
<h3>Importance</h3> The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. The epidemiology of discontinued RCTs, however, remains unclear. <h3>Objectives</h3> To determine the prevalence, characteristics, and publication history of discontinued RCTs and to investigate factors associated with RCT discontinuation due to poor recruitment and …