Multi-Arm Clinical Trials of New Agents: Some Design Considerations
Multi-Arm Clinical Trials of New Agents: Some Design Considerations
Abstract A major challenge in the development of anticancer therapies is the considerable time and resources needed for conducting randomized clinical trials (RCT). There is a need for more efficient RCT designs that accelerate development, minimize costs, and make trials more appealing to patients. We review the statistical and logistical …