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A deterministic model for influenza infection with multiple strains and antigenic drift

A deterministic model for influenza infection with multiple strains and antigenic drift

We describe a multiple strain Susceptible Infected Recovered deterministic model for the spread of an influenza subtype within a population. The model incorporates appearance of new strains due to antigenic drift, and partial immunity to reinfection with related circulating strains. It also includes optional seasonal forcing of the transmission rate …