Two-stage Adaptive Randomization for Delayed Response in Clinical Trials
Two-stage Adaptive Randomization for Delayed Response in Clinical Trials
Summary Despite the widespread use of equal randomization in clinical trials, response-adaptive randomization has attracted considerable interest. There is typically a prerun of equal randomization before the implementation of response-adaptive randomization, although it is often not clear how many subjects are needed in this prephase, and in practice the number …