Linking immunological and epidemiological dynamics of HIV: the case of super-infection
Linking immunological and epidemiological dynamics of HIV: the case of super-infection
In this paper, a two-strain model that links immunological and epidemiological dynamics across scales is formulated. On the within-host scale, the two strains eliminate each other with the strain with the larger immunological reproduction persisting. However, on the population scale superinfection is possible, with the strain with larger immunological reproduction …