Relative Risk Estimated from the Ratio of Two Median Unbiased Estimates
Relative Risk Estimated from the Ratio of Two Median Unbiased Estimates
Clinical trials often include binary endpoints. In some cases, no successes are observed and the usual large-sample estimates of relative risk are undefined. This paper proposes an estimator for relative risk based on the median unbiased estimator. The proposed relative risk estimator is well defined and performs satisfactorily for a …