Prefer a chat interface with context about you and your work?
Prediction of accrual closure date in multi‐center clinical trials with discrete‐time Poisson process models
In a phase III multi‐center cancer clinical trial or a large public health study, sample size is predetermined to achieve desired power, and study participants are enrolled from tens or hundreds of participating institutions. As the accrual is closing to the target size, the coordinating data center needs to project …