Response-Adaptive Randomization for Multi-arm Clinical Trials Using the Forward Looking Gittins Index Rule
Response-Adaptive Randomization for Multi-arm Clinical Trials Using the Forward Looking Gittins Index Rule
Summary The Gittins index provides a well established, computationally attractive, optimal solution to a class of resource allocation problems known collectively as the multi-arm bandit problem. Its development was originally motivated by the problem of optimal patient allocation in multi-arm clinical trials. However, it has never been used in practice, …