Informational Odds Ratio: A Useful Measure of Epidemiologic Association in Environment Exposure Studies

Jimmy T. Efird, Suzanne Lea, Amanda E. Toland, Christopher J. Phillips

Type: Article

Publication Date: 2012-01-01

Citations: 16

DOI: https://doi.org/10.4137/ehi.s9236

Abstract

The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility (ie, the combined crude ratio will not change after adjusting for a variable that is not a confounder). Adjusted traditional odds ratios (TORs) are not collapsible. In contrast, Mantel-Haenszel adjusted IORs generally are collapsible. IORs are a useful measure of disease association in environmental case-referent studies, especially when the disease is common in the exposed and/or unexposed groups.

Locations

Environmental Health Insights - View - PDF
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Europe PMC (PubMed Central) - View - PDF
DOAJ (DOAJ: Directory of Open Access Journals) - View
The Scholarship East Carolina University's Institutional Repository (East Carolina University) - View - PDF
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Works Cited by This (15)

Action	Title	Year	Authors
+	Collapsibility of Relative Risk in Contingency Tables with a Response Variable	1992	Zhi Geng
+	Test‐Based Exact Confidence Intervals for the Difference of Two Binomial Proportions	1999	Ivan S. F. Chan Zhongxin Zhang
+ PDF Chat	The Central Limit Theorem Around 1935	1986	Lucien Le Cam
+	Estimation of a Common Effect Parameter from Sparse Follow-Up Data	1985	Sander Greenland James M. Robins
+	The Relative Merits of Risk Ratios and Odds Ratios	2009	Peter Cummings
+	A Modified Poisson Regression Approach to Prospective Studies with Binary Data	2004	Guangyong Zou
+	A Note on the Efficiency of Sandwich Covariance Matrix Estimation	2001	Göran Kauermann Raymond J. Carroll
+ PDF Chat	Article Commentary: Dealing with Diversity in Computational Cancer Modeling	2013	David Johnson Steve McKeever Georgios Stamatakos Dimitra D. Dionysiou Norbert Graf Vangelis Sakkalis Kostas Marias Zhihui Wang Thomas S. Deisboeck
+	Obtaining Confidence Intervals for the Risk Ratio in Cohort Studies	1978	Daniela Katz Jorge Baptista Stanley P. Azen Malcolm C. Pike
+	Exact tests and exact confidence intervals for the ratio of two binomial proportions.	2003	Pralay Mukhopadhyay