The combination of randomized and historical controls in clinical trials

Stuart J. Pocock

Type: Review

Publication Date: 1976-03-01

Citations: 452

DOI: https://doi.org/10.1016/0021-9681(76)90044-8

View Publication

Locations

PubMed - View
Journal of Chronic Diseases - View

Similar Works

Action	Title	Year	Authors
+	Commentary on Harun et al.: The use of historical controls in randomized clinical trials	2023	Stephen L. George
+ PDF Chat	Retrospective versus prospective controls in clinical trials.	1980	Gerald J.M. Tevaarwerk
+	Reducing Patient Burden in Clinical Trials Through the Use of Historical Controls: Appropriate Selection of Historical Data to Minimize Risk of Bias	2019	Jessica Lim Li Wang Nicky Best Jeen Liu Jiacheng Yuan Florence H. Yong Lanju Zhang Rosalind Walley Alice Gosselin Robert Roebling
+	A Simple Approach to Incorporating Historical Control Data in Clinical Trial Design and Analysis	2022	Lanju Zhang Zailong Wang Li Wang Lu Cui Jeremy Sokolove Ivan S. F. Chan
+	Incorporation of historical data in the analysis of randomized therapeutic trials	2011	Charlotte Rietbergen Irene Klugkist Kristel J.M. Janssen Karel G.M. Moons Herbert Hoijtink
+	Randomized Clinical Trials	2014	Yoram Vodovotz Gary An
+	Selection of Control in Clinical Trials	2012	Irving K. Hwang
+	Selection of Control in Clinical Trials	2010	Irving K. Hwang
+	Selection of Control in Clinical Trials	2003	Irving Hwang
+	Using Historical Controls for Designing Phase II Clinical Trials [R package hctrial version 0.1.0]	2018	Dominic Edelmann
+	Experimental Design in Clinical Trials	2009
+	Experimental Design in Clinical Trials	2003
+	Experimental design in clinical trials	2023	Alexis Angelette Adrienne M. Murphy Fatima Iqbal Cade Bourgeois Grant Borne Lauren Rando Elyse M. Cornett Alan D. Kaye
+	The Randomized Controlled Clinical Trial	1992	David S. Salsburg
+ PDF Chat	Use of historical control data for assessing treatment effects in clinical trials	2014	Kert Viele Scott Berry Beat Neuenschwander Billy Amzal Fang Chen Nathan Enas Brian P. Hobbs Joseph G. Ibrahim Nelson Kinnersley Stacy Lindborg
+ PDF Chat	Controlled Clinical Trials	1978	David W. Alling Max Halperin James H. Ware
+	The cornerstones of randomized clinical trials	2024	Mercedes Gori Domenico Abelardo Annalisa Pitino Eleni Stamellou Adamantia Bratsiakou Carmela Marino G. Tripepi Stefanos Roumeliotis Graziella D’Arrigo
+	Nonrandomized controlled clinical trials	2025	Turki Al Garni Amr A. Arafat Bader Alqarni Abdulrahman Alqahtani
+	Improving the efficiency of clinical trial designs by using historical control data or adding a treatment arm to an ongoing trial	2018	Maxine Bennett
+	HOW VALID IS THE USE OF RETROSPECTIVE CONTROLS IN CLINICAL TRIALS?	1979

Works That Cite This (304)

Action	Title	Year	Authors
+	Repurposing historical control clinical trial data to provide safety context	2015	Prakash Bhuyan Jigar Desai Matthew St Louis Martin Carlsson Edward Bowen M. M. Danielson Michael Cantor
+ PDF Chat	Challenges of using external data in clinical trials- an illustration in patients with COVID-19	2022	Sylvie Chevret Jean‐François Timsit Lucie Biard
+ PDF Chat	Significance and limitations of randomization in clinical trials	2020	Satoshi Teramukai
+ PDF Chat	Introduction to Biostatistics	1995	Larry Winner
+ PDF Chat	Bayesian Dynamic Borrowing of Historical Information with Applications to the Analysis of Large-Scale Assessments	2022	David Kaplan Jianshen Chen Sinan Yavuz Weicong Lyu
+ PDF Chat	Improving efficiency of inference in clinical trials with external control data	2021	Xinyu Li Wang Miao Fang Lü Xiao‐Hua Zhou
+	Designing historical control studies with survival endpoints using exact statistical inference	2020	Gang Han
+ PDF Chat	Statistics in question: assessing clinical trials--design II.	1981	S M Gore
+	Basic Study Design	1998	Lawrence M. Friedman Curt D. Furberg David L. DeMets
+	A Simple Approach to Incorporating Historical Control Data in Clinical Trial Design and Analysis	2022	Lanju Zhang Zailong Wang Li Wang Lu Cui Jeremy Sokolove Ivan S. F. Chan

Works Cited by This (5)

Action	Title	Year	Authors
+	The Design of Experiments	1935	Ronald Aylmer Fisher
+	Non-Randomized Controls in Cancer Clinical Trials	1974	Edmund A. Gehan Emil J. Freireich
+	Controlled Studies in Clinical Cancer Research	1972	Thomas C. Chalmers Jerome B. Block Stephanie J. Lee
+	Statistical Methods in Clinical and Preventive Medicine	1962	Adam Hill
+	The Determination of Sample Sizes for Use with the Exact Conditional Test in 2 x 2 Comparative Trials	1973	Mitchell H. Gail John J. Gart