Type: Article
Publication Date: 2007-06-20
Citations: 106
DOI: https://doi.org/10.1073/pnas.0700324104
Recent experimental studies indicate that synaptic changes induced by neuronal activity are discrete jumps between a small number of stable states. Learning in systems with discrete synapses is known to be a computationally hard problem. Here, we study a neurobiologically plausible on-line learning algorithm that derives from Belief Propagation algorithms. We show that it performs remarkably well in a model neuron with binary synapses, and a finite number of `hidden' states per synapse, that has to learn a random classification task. Such system is able to learn a number of associations close to the theoretical limit, in time which is sublinear in system size. This is to our knowledge the first on-line algorithm that is able to achieve efficiently a finite number of patterns learned per binary synapse. Furthermore, we show that performance is optimal for a finite number of hidden states which becomes very small for sparse coding. The algorithm is similar to the standard `perceptron' learning algorithm, with an additional rule for synaptic transitions which occur only if a currently presented pattern is `barely correct'. In this case, the synaptic changes are meta-plastic only (change in hidden states and not in actual synaptic state), stabilizing the synapse in its current state. Finally, we show that a system with two visible states and K hidden states is much more robust to noise than a system with K visible states. We suggest this rule is sufficiently simple to be easily implemented by neurobiological systems or in hardware.