Y. H. George

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All published works

Action	Title	Year	Authors
+	Statistics In the Pharmaceutical Industry	2019	Ronald J. Bosch C. Ralph Buncher Shein‐Chung Chow Satya D. Dubey J. Y. Tsay Charles W. Dunnett P.H. van Ewijk Roger E. Flora Paul S. Horn Irving K. Hwang
+	Active Control Trials	2018	Y. H. George Gang Chen Mark Rothmann Ning Li
+	Inferiority Index, Margin Functions, and Hybrid Designs for Noninferiority Trials with Binary Outcomes	2015	Y. H. George
+	Understanding the FDA Guidance on Adaptive Designs: Historical, Legal, and Statistical Perspectives	2010	Qing Liu Y. H. George
+	Active Control Trials	2010	Y. H. George Gang Chen Mark Rothmann Ning Li
+	A method for testing a prespecified subgroup in clinical trials	2007	Yang Song Y. H. George
+	George Chi's Discussion of the “Executive Summary of the PhRMA Working Group on Adaptive Designs in Clinical Drug Development” By Christy Chuang-Stein, Vladimir Dragalin, Brenda Gaydos, Michael Krams, and José Pinheiro	2006	Y. H. George
+	Evaluation of Health-Related Quality-of-Life Measures in Oncology Drug Product Applications: Issues and Concerns	2004	Rajeshwari Sridhara Gang Chen Y. H. George Donna Griebel
+	Design and analysis of non‐inferiority mortality trials in oncology	2002	Mark Rothmann Ning Li Gang Chen Y. H. George Robert Temple Hsiao‐Hui Tsou
+	On Sample Size and Inference for Two‐Stage Adaptive Designs	2001	Qing Liu Y. H. George
+	THE ATTRACTIVENESS OF THE CONCEPT OF A PROSPECTIVELY DESIGNED TWO-STAGE CLINICAL TRIAL	1999	Y. H. George Qing Liu
+	Multiple Testings: Multiple Comparisons and Multiple Endpoints	1998	Y. H. George
+	Response Surface and Factorial Designs for Combination Antihypertensive Drugs	1990	H. M. James Hung Tie‐Hua Ng Y. H. George Raymond J. Lipicky

Common Coauthors

Coauthor	Papers Together
Mark Rothmann	3
Qing Liu	1
Wen Jen Chen	1
Weichung Joe Shih	1
Roswitha Kelly	1
Donna Griebel	1
Hsiao‐Hui Tsou	1
Tie‐Hua Ng	1
Yi Tsong	1
T. Timothy Chen	1
Ronald J. Bosch	1
Ching-Cheng Shen	1
Roger E. Flora	1
Raymond J. Lipicky	1
Paul S. Horn	1
Shein‐Chung Chow	1
Amadeo J. Pesce	1
Yusong Chen	1
K. K. Gordon Lan	1
Cynthia McCormick	1
Q. Liu	1
Mamoru Narukawa	1
Irving K. Hwang	1
J. Y. Tsay	1
Lianng Yuh	1
Daphne T. Lin	1
Masahiro Takeuchi	1
Charles W. Dunnett	1
Chi‐wan Chen	1
H. M. James Hung	1
C. Ralph Buncher	1
Robert T. O’Neill	1
Gang Chen	1
Qing Liu	1
Ning Li	1
Ning Li	1
Gang Chen	1
Gang Chen	1
Gang Chen	1
Qing Liu	1
Yang Song	1
Kim E. Zerba	1
John Constant	1
Karl K. Lin	1
Charles Goldsmith	1
Bernhard Huitfeldt	1
Ted M. Smith	1
Gordon Pledger	1
Rajeshwari Sridhara	1
Mirza Ali	1

Commonly Cited References

Action	Title	Year	Authors	# of times referenced
+	Designed Extension of Studies Based on Conditional Power	1995	Michael A. Proschan Sally Hunsberger	4
+	Nonparametric Analysis of Covariance and Its Role in Noninferiority Clinical Trials	1999	Gary G. Koch Catherine M. Tangen	3
+	ESTABLISHING EQUIVALENCE BY SHOWING THAT A SPECIFIED PERCENTAGE OF THE EFFECT OF THE ACTIVE CONTROL OVER PLACEBO IS MAINTAINED	1999	Eric Holmgren	3
+	Statistical Inference for Self‐Designing Clinical Trials with a One‐Sided Hypothesis	1999	Yu Shen Lloyd D. Fisher	3
+	A Simple Sequentially Rejective Multiple Test Procedure	1979	Sture Holm	3
+	Some Issues in the Design and Analysis of Equivalence Trials	1999	Walter W. Hauck Sharon Anderson	3
+	Self-designing clinical trials	1998	Lloyd D. Fisher	3
+	A Comparison of Two Methods for Adaptive Interim Analyses in Clinical Trials	1998	Gernot Wassmer	3
+	Evaluation of Experiments with Adaptive Interim Analyses	1994	Péter Bauer Karl Kohne	3
+	New designs for the selection of treatments to be tested in randomized clinical trials	1994	Richard Simon Peter F. Thall Susan S. Ellenberg	2
+	Sample size re-estimation without unblinding for normally distributed outcomes with unknown variance	1992	A. Lawrence Gould Weichung Joseph Shih	2
+ PDF Chat	Optimal two-stage designs for phase II clinical trials	1989	Richard Simon	2
+	Issues with Statistical Risks for Testing Methods in Noninferiority Trial Without a Placebo ARM	2007	Hung Hung Sue‐Jane Wang Robert T. O’Neill	2
+	Utility and pitfalls of some statistical methods in active controlled clinical trials	2002	Sue‐Jane Wang Hung Hung Yi Tsong	2
+	“Proving the null hypothesis” in clinical trials	1982	William C. Blackwelder	2
+	Testing Whether an Identified Treatment Is Best	1989	Eugene Laska Morris Meisner	2
+	Design and analysis of non‐inferiority mortality trials in oncology	2002	Mark Rothmann Ning Li Gang Chen Y. H. George Robert Temple Hsiao‐Hui Tsou	2
+	The role of internal pilot studies in increasing the efficiency of clinical trials	1990	Janet Wittes Erica Brittain	2
+	Biopharmaceutical Sequential Statistical Applications.	1993	Keith E. Muller Karl E. Peace	2
+	Multiple testing in clinical trials	1991	Péter Bauer	2
+	Two-Stage Clinical Trial Stopping Rules	1984	Janet D. Elashoff Terry J. Reedy	2
+	Optimization of Multistage Testing Times and Critical Values in Clinical Trials	1993	ERICA BRITTAIN Kent R. Bailey	2
+	On closed testing procedures with special reference to ordered analysis of variance	1976	Ruth Marcus Eric Peritz K. R. Gabriel	2
+	Problems in interpreting active control equivalence trials	1996	Robert Temple	2
+	Modification of Sample Size in Group Sequential Clinical Trials	1999	Lu Cui H. M. James Hung Sue‐Jane Wang	2
+	Challenges and regulatory experiences with non‐inferiority trial design without placebo arm	2009	Hung Hung Sue‐Jane Wang Robert T. O’Neill	2
+	A stagewise rejective multiple test procedure based on a modified Bonferroni test	1988	Gerhard Hommel	2
+	Hypotheses and Type I Error in Active-Control Noninferiority Trials	2004	Gang Chen Yongcheng Wang George YH.	2
+	Some fundamental issues with non‐inferiority testing in active controlled trials	2002	Hung Hung Sue‐Jane Wang Yi Tsong John Lawrence Robert T. O'Neil	2
+	A Ratio Test in Active Control Non-Inferiority Trials with a Time-to-Event Endpoint	2006	Yongcheng Wang Gang Chen George Y.H.	2
+	Noninferiority hypotheses and choice of noninferiority margin	2008	Tie‐Hua Ng	2
+	Planned versus attained design in phase II clinical trials	1992	Stephanie Green Steve Dahlberg	2
+	On Sample Size and Inference for Two‐Stage Adaptive Designs	2001	Qing Liu Y. H. George	2
+	Likelihood ratio and a Bayesian approach were superior to standard noninferiority analysis when the noninferiority margin varied with the control event rate	2004	Mimi Kim Xiaonan Xue	1
+	Comparison of several model-based methods for analysing incomplete quality of life data in cancer clinical trials	1998	Diane L. Fairclough Harriet F. Peterson David Cella P. Bonomi	1
+	On changing a long‐term clinical trial midstream	2002	Janet Wittes	1
+	Bayesian Analysis and the GUSTO Trial	1995	Richard Browne	1
+	Multiple Imputation for Interval Estimation from Simple Random Samples with Ignorable Nonresponse	1986	Donald B. Rubin Nathaniel Schenker	1
+	Monitoring of the data for evidence of adverse or beneficial treatment effects	1983	Paul L. Canner	1
+	Discrete sequential boundaries for clinical trials	1983	K. K. Gordon Lan David L. DeMets	1
+	A reviewer's perspective on multiple endpoint issues in clinical trials	1997	Mohammad F. Huque Abdul J. Sankoh	1
+ PDF Chat	Pattern-Mixture Models for Multivariate Incomplete Data	1993	Roderick J. A. Little	1
+	Placebo-Controlled Trials and Active-Control Trials in the Evaluation of New Treatments. Part 1: Ethical and Scientific Issues	2000	Robert Temple	1
+	Innovative Approaches for Designing and Analyzing Adaptive Dose-Ranging Trials	2007	Björn Bornkamp Frank Bretz Alex Dmitrienko Greg Enas Brenda Gaydos Chyi‐Hung Hsu Franz König Michael Krams Qing Liu Beat Neuenschwander	1
+	Subgroup analyses in randomized trials: risks of subgroup-specific analyses;	2004	Sara Brookes Elise Whitely Matthias Egger George Davey Smith Paul A. Mulheran T. J. Peters	1
+	Data Monitoring Committees in Clinical Trials: A Practical Perspective	2002	Susan S. Ellenberg Thomas R. Fleming David L. DeMets	1
+	Internal pilot studies I: type I error rate of the naivet-test	1999	Janet Wittes Oliver Schabenberger David M. Zucker Erica Brittain Michael A. Proschan	1
+	On design and inference for two-stage adaptive clinical trials with dependent data	2005	Qing Liu Gordon Pledger	1
+	Optimally weighted, fixed sequence and gatekeeper multiple testing procedures	2001	Peter H. Westfall Alok Krishen	1
+	THE ATTRACTIVENESS OF THE CONCEPT OF A PROSPECTIVELY DESIGNED TWO-STAGE CLINICAL TRIAL	1999	Y. H. George Qing Liu	1